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Gene PIK3CA
Variant G463_N465del
Impact List deletion
Protein Effect unknown
Gene Variant Descriptions PIK3CA G463_N465del results in the deletion of three amino acids in the C2 PI3K-type domain of the Pik3ca protein from amino acids 463 to 465 (UniProt.org). G463_N465del has not been characterized in the scientific literature and therefore, its effect on Pik3ca protein function is unknown (PubMed, Jun 2024).
Associated Drug Resistance
Category Variants Paths

PIK3CA mutant PIK3CA exon8 PIK3CA G463_N465del

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Transcript NM_006218.4
gDNA chr3:g.179210321_179210329delGGATCAAAT
cDNA c.1387_1395delGGATCAAAT
Protein p.G463_N465del
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_006218.4 chr3:g.179210321_179210329delGGATCAAAT c.1387_1395delGGATCAAAT p.G463_N465del RefSeq GRCh38/hg38
XM_006713658.5 chr3:g.179210321_179210329delGGATCAAAT c.1387_1395delGGATCAAAT p.G463_N465del RefSeq GRCh38/hg38

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References