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Gene | PIK3CA |
Variant | G463_N465del |
Impact List | deletion |
Protein Effect | unknown |
Gene Variant Descriptions | PIK3CA G463_N465del results in the deletion of three amino acids in the C2 PI3K-type domain of the Pik3ca protein from amino acids 463 to 465 (UniProt.org). G463_N465del has not been characterized in the scientific literature and therefore, its effect on Pik3ca protein function is unknown (PubMed, Jun 2024). |
Associated Drug Resistance | |
Category Variants Paths |
PIK3CA mutant PIK3CA exon8 PIK3CA G463_N465del |
Transcript | NM_006218.4 |
gDNA | chr3:g.179210321_179210329delGGATCAAAT |
cDNA | c.1387_1395delGGATCAAAT |
Protein | p.G463_N465del |
Source Database | RefSeq |
Genome Build | GRCh38/hg38 |
Transcript | gDNA | cDNA | Protein | Source Database | Genome Build |
---|---|---|---|---|---|
XM_006713658.5 | chr3:g.179210321_179210329delGGATCAAAT | c.1387_1395delGGATCAAAT | p.G463_N465del | RefSeq | GRCh38/hg38 |
NM_006218.4 | chr3:g.179210321_179210329delGGATCAAAT | c.1387_1395delGGATCAAAT | p.G463_N465del | RefSeq | GRCh38/hg38 |
Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
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