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| Gene | PIK3CA |
| Variant | G364A |
| Impact List | missense |
| Protein Effect | unknown |
| Gene Variant Descriptions | PIK3CA G364A lies within the C2 PI3K-type domain of the Pik3ca protein (UniProt.org). G364A has been identified in sequencing studies (PMID: 30393068), but has not been biochemically characterized and therefore, its effect on Pik3ca protein function is unknown (PubMed, Dec 2025). |
| Associated Drug Resistance | |
| Category Variants Paths |
PIK3CA mutant PIK3CA G364A |
| Transcript | NM_006218.4 |
| gDNA | chr3:g.179204534G>C |
| cDNA | c.1091G>C |
| Protein | p.G364A |
| Source Database | RefSeq |
| Genome Build | GRCh38/hg38 |
| Transcript | gDNA | cDNA | Protein | Source Database | Genome Build |
|---|---|---|---|---|---|
| NM_006218.3 | chr3:g.179204534G>C | c.1091G>C | p.G364A | RefSeq | GRCh38/hg38 |
| NM_006218.4 | chr3:g.179204534G>C | c.1091G>C | p.G364A | RefSeq | GRCh38/hg38 |
| XM_006713658.4 | chr3:g.179204534G>C | c.1091G>C | p.G364A | RefSeq | GRCh38/hg38 |
| XM_006713658.5 | chr3:g.179204534G>C | c.1091G>C | p.G364A | RefSeq | GRCh38/hg38 |
| XM_011512894.2 | chr3:g.179204534G>C | c.1091G>C | p.G364A | RefSeq | GRCh38/hg38 |
| Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
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