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Gene CTNNB1
Variant N387I
Impact List missense
Protein Effect unknown
Gene Variant Descriptions CTNNB1 N387I lies within ARM repeat 6 of the Ctnnb1 protein (UniProt.org). N387I has been identified in sequencing studies (PMID: 29937994, PMID: 31560893), but has not been biochemically characterized and therefore, its effect on Ctnnb1 protein function is unknown (PubMed, Jul 2024).
Associated Drug Resistance
Category Variants Paths

CTNNB1 mutant CTNNB1 N387I

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Transcript NM_001098210.2
gDNA chr3:g.41233419A>T
cDNA c.1160A>T
Protein p.N387I
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
XM_017005738.2 chr3:g.41233419A>T c.1160A>T p.N387I RefSeq GRCh38/hg38
NM_001904.3 chr3:g.41233419A>T c.1160A>T p.N387I RefSeq GRCh38/hg38
XM_006712985.1 chr3:g.41233419A>T c.1160A>T p.N387I RefSeq GRCh38/hg38
XM_006712985.2 chr3:g.41233419A>T c.1160A>T p.N387I RefSeq GRCh38/hg38
XM_047447477.1 chr3:g.41233419A>T c.1160A>T p.N387I RefSeq GRCh38/hg38
XM_024453356.1 chr3:g.41233419A>T c.1160A>T p.N387I RefSeq GRCh38/hg38
NM_001098209.2 chr3:g.41233419A>T c.1160A>T p.N387I RefSeq GRCh38/hg38
NM_001098210.1 chr3:g.41233419A>T c.1160A>T p.N387I RefSeq GRCh38/hg38
XM_024453357.1 chr3:g.41233419A>T c.1160A>T p.N387I RefSeq GRCh38/hg38
XM_047447480.1 chr3:g.41233419A>T c.1160A>T p.N387I RefSeq GRCh38/hg38
XM_024453358.1 chr3:g.41233419A>T c.1160A>T p.N387I RefSeq GRCh38/hg38
XM_047447479.1 chr3:g.41233419A>T c.1160A>T p.N387I RefSeq GRCh38/hg38
NM_001098210.2 chr3:g.41233419A>T c.1160A>T p.N387I RefSeq GRCh38/hg38
XM_047447483.1 chr3:g.41233419A>T c.1160A>T p.N387I RefSeq GRCh38/hg38
NM_001098209.1 chr3:g.41233419A>T c.1160A>T p.N387I RefSeq GRCh38/hg38
XM_024453356.2 chr3:g.41233419A>T c.1160A>T p.N387I RefSeq GRCh38/hg38
XM_047447478.1 chr3:g.41233419A>T c.1160A>T p.N387I RefSeq GRCh38/hg38
XM_017005738.1 chr3:g.41233419A>T c.1160A>T p.N387I RefSeq GRCh38/hg38
NM_001904.4 chr3:g.41233419A>T c.1160A>T p.N387I RefSeq GRCh38/hg38
XM_047447481.1 chr3:g.41233419A>T c.1160A>T p.N387I RefSeq GRCh38/hg38

Filtering

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  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

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  • Click on any column header arrows to sort by that column
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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References