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Gene CTNNB1
Variant T41_S45del
Impact List deletion
Protein Effect unknown
Gene Variant Descriptions CTNNB1 T41_S45del results in the deletion of five amino acids of the Ctnnb1 protein from amino acids 41 to 45 (UniProt.org). T41_S45del has not been characterized in the scientific literature and therefore, its effect on Ctnnb1 protein function is unknown (PubMed, Jul 2024).
Associated Drug Resistance
Category Variants Paths

CTNNB1 mutant CTNNB1 T41_S45del

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Transcript NM_001098210.2
gDNA chr3:g.41224633_41224647del15
cDNA c.121_135del15
Protein p.T41_S45delTTAPS
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_001330729.2 chr3:g.41224655_41224669del15 c.122_136del15 p.G41_P45delGKGNP RefSeq GRCh38/hg38
XM_047447482.1 chr3:g.41224655_41224669del15 c.122_136del15 p.G41_P45delGKGNP RefSeq GRCh38/hg38
NM_001098209.1 chr3:g.41224633_41224647del15 c.121_135del15 p.T41_S45del RefSeq GRCh38/hg38
XM_047447483.1 chr3:g.41224633_41224647del15 c.121_135del15 p.T41_S45delTTAPS RefSeq GRCh38/hg38
XM_006712985.2 chr3:g.41224633_41224647del15 c.121_135del15 p.T41_S45delTTAPS RefSeq GRCh38/hg38
XM_006712985.1 chr3:g.41224633_41224647del15 c.121_135del15 p.T41_S45del RefSeq GRCh38/hg38
XM_024453356.1 chr3:g.41224633_41224647del15 c.121_135del15 p.T41_S45del RefSeq GRCh38/hg38
XM_047447478.1 chr3:g.41224633_41224647del15 c.121_135del15 p.T41_S45delTTAPS RefSeq GRCh38/hg38
XM_047447479.1 chr3:g.41224633_41224647del15 c.121_135del15 p.T41_S45delTTAPS RefSeq GRCh38/hg38
NM_001904.4 chr3:g.41224633_41224647del15 c.121_135del15 p.T41_S45delTTAPS RefSeq GRCh38/hg38
NM_001098209.2 chr3:g.41224633_41224647del15 c.121_135del15 p.T41_S45delTTAPS RefSeq GRCh38/hg38
XM_047447480.1 chr3:g.41224633_41224647del15 c.121_135del15 p.T41_S45delTTAPS RefSeq GRCh38/hg38
XM_024453358.1 chr3:g.41224633_41224647del15 c.121_135del15 p.T41_S45del RefSeq GRCh38/hg38
XM_047447477.1 chr3:g.41224633_41224647del15 c.121_135del15 p.T41_S45delTTAPS RefSeq GRCh38/hg38
NM_001098210.1 chr3:g.41224633_41224647del15 c.121_135del15 p.T41_S45del RefSeq GRCh38/hg38
NM_001098210.2 chr3:g.41224633_41224647del15 c.121_135del15 p.T41_S45delTTAPS RefSeq GRCh38/hg38
NM_001904.3 chr3:g.41224633_41224647del15 c.121_135del15 p.T41_S45del RefSeq GRCh38/hg38
XM_047447481.1 chr3:g.41224633_41224647del15 c.121_135del15 p.T41_S45delTTAPS RefSeq GRCh38/hg38
XM_017005738.1 chr3:g.41224633_41224647del15 c.121_135del15 p.T41_S45del RefSeq GRCh38/hg38
XM_024453357.1 chr3:g.41224633_41224647del15 c.121_135del15 p.T41_S45del RefSeq GRCh38/hg38
XM_017005738.2 chr3:g.41224633_41224647del15 c.121_135del15 p.T41_S45delTTAPS RefSeq GRCh38/hg38
XM_024453356.2 chr3:g.41224633_41224647del15 c.121_135del15 p.T41_S45delTTAPS RefSeq GRCh38/hg38

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References