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Gene FBXW7
Variant D520V
Impact List missense
Protein Effect unknown
Gene Variant Descriptions FBXW7 D520V lies within WD repeat 4 of the Fbxw7 protein (UniProt.org). D520V has not been characterized in the scientific literature and therefore, its effect on Fbxw7 protein function is unknown (PubMed, Aug 2024).
Associated Drug Resistance
Category Variants Paths

FBXW7 mutant FBXW7 D520V

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Transcript NM_033632.3
gDNA chr4:g.152326091T>A
cDNA c.1559A>T
Protein p.D520V
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
XM_024454121.1 chr4:g.152326091T>A c.1559A>T p.D520V RefSeq GRCh38/hg38
XM_011532084.2 chr4:g.152326091T>A c.1559A>T p.D520V RefSeq GRCh38/hg38
NM_001349798.1 chr4:g.152326091T>A c.1559A>T p.D520V RefSeq GRCh38/hg38
XM_011532084.3 chr4:g.152326091T>A c.1559A>T p.D520V RefSeq GRCh38/hg38
NM_033632.3 chr4:g.152326091T>A c.1559A>T p.D520V RefSeq GRCh38/hg38
NM_018315.4 chr4:g.152324240T>A c.1559A>T p.D520V RefSeq GRCh38/hg38
XM_047415899.1 chr4:g.152326091T>A c.1559A>T p.D520V RefSeq GRCh38/hg38
NM_018315.5 chr4:g.152324240T>A c.1559A>T p.D520V RefSeq GRCh38/hg38
XM_024454123.1 chr4:g.152326091T>A c.1559A>T p.D520V RefSeq GRCh38/hg38
XM_024454122.1 chr4:g.152326091T>A c.1559A>T p.D520V RefSeq GRCh38/hg38
XM_011532085.3 chr4:g.152326091T>A c.1559A>T p.D520V RefSeq GRCh38/hg38
XM_047415900.1 chr4:g.152326091T>A c.1559A>T p.D520V RefSeq GRCh38/hg38
NM_001349798.2 chr4:g.152326091T>A c.1559A>T p.D520V RefSeq GRCh38/hg38
XM_011532085.2 chr4:g.152326091T>A c.1559A>T p.D520V RefSeq GRCh38/hg38
XM_047415898.1 chr4:g.152326091T>A c.1559A>T p.D520V RefSeq GRCh38/hg38
XM_024454123.2 chr4:g.152326091T>A c.1559A>T p.D520V RefSeq GRCh38/hg38
NM_033632.3 chr4:g.152326091T>A c.1559A>T p.D520V RefSeq GRCh38/hg38
XM_024454124.1 chr4:g.152326091T>A c.1559A>T p.D520V RefSeq GRCh38/hg38
XM_047415897.1 chr4:g.152326091T>A c.1559A>T p.D520V RefSeq GRCh38/hg38
XM_047415901.1 chr4:g.152326091T>A c.1559A>T p.D520V RefSeq GRCh38/hg38

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Molecular Profile Protein Effect Treatment Approaches
FBXW7 D520V unknown