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Gene | FBXW7 |
Variant | T385P |
Impact List | missense |
Protein Effect | unknown |
Gene Variant Descriptions | FBXW7 T385P lies within WD repeat 1 of the Fbxw7 protein (UniProt.org). T385P has been identified in sequencing studies (PMID: 26802149), but has not been biochemically characterized and therefore, its effect on Fbxw7 protein function is unknown (PubMed, Jun 2025). |
Associated Drug Resistance | |
Category Variants Paths |
FBXW7 mutant FBXW7 T385P |
Transcript | NM_001349798.2 |
gDNA | chr4:g.152329755T>G |
cDNA | c.1153A>C |
Protein | p.T385P |
Source Database | RefSeq |
Genome Build | GRCh38/hg38 |