PIK3CA I112_L113del
Gene Variant Detail

Request Content

Contact

Missing content? – Request curation!

Request curation for specific Genes, Variants, or PubMed publications.

Have questions, comments, or suggestions? - Let us know!

Email us at : ckbsupport@genomenon.com

Gene PIK3CA
Variant I112_L113del
Impact List deletion
Protein Effect unknown
Gene Variant Descriptions PIK3CA I112_L113del results in the deletion of two amino acids of the Pik3ca protein from amino acids 112 to 113 (UniProt.org). I112_L113del has not been characterized and therefore, its effect on Pik3ca protein function is unknown (PubMed, Mar 2026).
Associated Drug Resistance
Category Variants Paths

PIK3CA mutant PIK3CA I112_L113del

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Transcript NM_006218.4
gDNA chr3:g.179199160_179199165delTCCTCA
cDNA c.335_340delTCCTCA
Protein p.I112_L113delIL
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
XM_011512894.2 chr3:g.179199160_179199165delTCCTCA c.335_340delTCCTCA p.I112_L113del RefSeq GRCh38/hg38
XM_006713658.5 chr3:g.179199160_179199165delTCCTCA c.335_340delTCCTCA p.I112_L113delIL RefSeq GRCh38/hg38
NM_006218.4 chr3:g.179199160_179199165delTCCTCA c.335_340delTCCTCA p.I112_L113delIL RefSeq GRCh38/hg38
XM_006713658.4 chr3:g.179199160_179199165delTCCTCA c.335_340delTCCTCA p.I112_L113del RefSeq GRCh38/hg38
NM_006218.3 chr3:g.179199160_179199165delTCCTCA c.335_340delTCCTCA p.I112_L113del RefSeq GRCh38/hg38

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References