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Gene PIK3CA
Variant K111_I112del
Impact List deletion
Protein Effect unknown
Gene Variant Descriptions PIK3CA K111_I112del results in the deletion of two amino acids of the Pik3ca protein from amino acids 111 to 112 (UniProt.org). K111_I112del has not been characterized in the scientific literature and therefore, its effect on Pik3ca protein function is unknown (PubMed, Aug 2024).
Associated Drug Resistance
Category Variants Paths

PIK3CA mutant PIK3CA K111_I112del

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Transcript NM_006218.4
gDNA chr3:g.179199156_179199161delAAGATC
cDNA c.331_336delAAGATC
Protein p.K111_I112delKI
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_006218.4 chr3:g.179199156_179199161delAAGATC c.331_336delAAGATC p.K111_I112delKI RefSeq GRCh38/hg38
XM_006713658.4 chr3:g.179199156_179199161delAAGATC c.331_336delAAGATC p.K111_I112del RefSeq GRCh38/hg38
NM_006218.3 chr3:g.179199156_179199161delAAGATC c.331_336delAAGATC p.K111_I112del RefSeq GRCh38/hg38
XM_006713658.5 chr3:g.179199156_179199161delAAGATC c.331_336delAAGATC p.K111_I112delKI RefSeq GRCh38/hg38
XM_011512894.2 chr3:g.179199156_179199161delAAGATC c.331_336delAAGATC p.K111_I112del RefSeq GRCh38/hg38

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  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References