Missing content? – Request curation!
Request curation for specific Genes, Variants, or PubMed publications.
Have questions, comments, or suggestions? - Let us know!
Email us at : ckbsupport@genomenon.com
| Gene | HRAS |
| Variant | G13N |
| Impact List | missense |
| Protein Effect | unknown |
| Gene Variant Descriptions | HRAS G13N lies within the GTP nucleotide binding region of the Hras protein (UniProt.org). G13N has been identified in sequencing studies (PMID: 34424952), but has not been biochemically characterized and therefore, its effect on Hras protein function is unknown (PubMed, Sep 2025). |
| Associated Drug Resistance | |
| Category Variants Paths |
HRAS mutant HRAS G13X HRAS G13N |
| Transcript | NM_005343.4 |
| gDNA | chr11:g.534285_534286delGGinsAA |
| cDNA | c.37_38delGGinsAA |
| Protein | p.G13N |
| Source Database | RefSeq |
| Genome Build | GRCh38/hg38 |
| Transcript | gDNA | cDNA | Protein | Source Database | Genome Build |
|---|---|---|---|---|---|
| NM_176795.4 | chr11:g.534285_534286delGGinsAA | c.37_38delGGinsAA | p.G13N | RefSeq | GRCh38/hg38 |
| NM_176795.5 | chr11:g.534285_534286delGGinsAA | c.37_38delGGinsAA | p.G13N | RefSeq | GRCh38/hg38 |
| NM_001130442.3 | chr11:g.534285_534286delGGinsAA | c.37_38delGGinsAA | p.G13N | RefSeq | GRCh38/hg38 |
| NM_001130442.2 | chr11:g.534285_534286delGGinsAA | c.37_38delGGinsAA | p.G13N | RefSeq | GRCh38/hg38 |
| NM_005343.3 | chr11:g.534285_534286delGGinsAA | c.37_38delGGinsAA | p.G13N | RefSeq | GRCh38/hg38 |
| NM_005343.4 | chr11:g.534285_534286delGGinsAA | c.37_38delGGinsAA | p.G13N | RefSeq | GRCh38/hg38 |
| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|