Gene Variant Detail

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Gene HRAS
Variant G13N
Impact List missense
Protein Effect unknown
Gene Variant Descriptions HRAS G13N lies within the GTP nucleotide binding region of the Hras protein (UniProt.org). G13N has been identified in sequencing studies (PMID: 34424952), but has not been biochemically characterized and therefore, its effect on Hras protein function is unknown (PubMed, Jun 2024).
Associated Drug Resistance
Category Variants Paths

HRAS mutant HRAS G13X HRAS G13N

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Transcript NM_005343.4
gDNA chr11:g.534285_534286delGGinsAA
cDNA c.37_38delGGinsAA
Protein p.G13N
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_001130442.3 chr11:g.534285_534286delGGinsAA c.37_38delGGinsAA p.G13N RefSeq GRCh38/hg38
NM_001130442.2 chr11:g.534285_534286delGGinsAA c.37_38delGGinsAA p.G13N RefSeq GRCh38/hg38
NM_176795.5 chr11:g.534285_534286delGGinsAA c.37_38delGGinsAA p.G13N RefSeq GRCh38/hg38
NM_005343.3 chr11:g.534285_534286delGGinsAA c.37_38delGGinsAA p.G13N RefSeq GRCh38/hg38
NM_176795.4 chr11:g.534285_534286delGGinsAA c.37_38delGGinsAA p.G13N RefSeq GRCh38/hg38
NM_005343.4 chr11:g.534285_534286delGGinsAA c.37_38delGGinsAA p.G13N RefSeq GRCh38/hg38

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References