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Gene PIK3CA
Variant W11_H14delinsY
Impact List indel
Protein Effect unknown
Gene Variant Descriptions PIK3CA W11_H14delinsY results in a deletion of four amino acids of the Pik3ca protein from amino acids 11 to 14, combined with the insertion of a tyrosine (Y) at the same site (UniProt.org). W11_H14delinsY has not been characterized in the scientific literature and therefore, its effect on Pik3ca protein function is unknown (PubMed, Mar 2024).
Associated Drug Resistance
Category Variants Paths

PIK3CA mutant PIK3CA W11_H14delinsY

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Transcript NM_006218.4
gDNA chr3:g.179198857_179198865delGGGGCATCC
cDNA c.32_40delGGGGCATCC
Protein p.W11_H14delinsY
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
XM_006713658.4 chr3:g.179198857_179198865delGGGGCATCC c.32_40delGGGGCATCC p.W11_H14delinsY RefSeq GRCh38/hg38
XM_011512894.2 chr3:g.179198857_179198865delGGGGCATCC c.32_40delGGGGCATCC p.W11_H14delinsY RefSeq GRCh38/hg38
NM_006218.3 chr3:g.179198857_179198865delGGGGCATCC c.32_40delGGGGCATCC p.W11_H14delinsY RefSeq GRCh38/hg38
NM_006218.4 chr3:g.179198857_179198865delGGGGCATCC c.32_40delGGGGCATCC p.W11_H14delinsY RefSeq GRCh38/hg38
XM_006713658.5 chr3:g.179198857_179198865delGGGGCATCC c.32_40delGGGGCATCC p.W11_H14delinsY RefSeq GRCh38/hg38

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  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References