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Gene NRAS
Variant G13F
Impact List missense
Protein Effect unknown
Gene Variant Descriptions NRAS G13F lies within a GTP-binding region of the Nras protein (UniProt.org). G13F has been identified in sequencing studies (PMID: 26189770), but has not been biochemically characterized and therefore, its effect on Nras protein function is unknown (PubMed, Dec 2023).
Associated Drug Resistance
Category Variants Paths

NRAS mutant NRAS exon2 NRAS G13X NRAS G13F

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Transcript NM_002524.5
gDNA chr1:g.114716123_114716124delGGinsTT
cDNA c.37_38delGGinsTT
Protein p.G13F
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_002524.4 chr1:g.114716123_114716124delGGinsTT c.37_38delGGinsTT p.G13F RefSeq GRCh38/hg38
NM_002524.5 chr1:g.114716123_114716124delGGinsTT c.37_38delGGinsTT p.G13F RefSeq GRCh38/hg38

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References