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Gene JAK2
Variant S958Y
Impact List missense
Protein Effect unknown
Gene Variant Descriptions JAK2 S958Y lies within protein kinase domain 2 of the Jak2 protein (UniProt.org). S958Y has not been characterized in the scientific literature and therefore, its effect on Jak2 protein function is unknown (PubMed, Apr 2024).
Associated Drug Resistance
Category Variants Paths

JAK2 mutant JAK2 S958Y

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Transcript NM_004972.4
gDNA chr9:g.5090557C>A
cDNA c.2873C>A
Protein p.S958Y
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_001322194.1 chr9:g.5090557C>A c.2873C>A p.S958Y RefSeq GRCh38/hg38
NM_001322196.1 chr9:g.5090557C>A c.2873C>A p.S958Y RefSeq GRCh38/hg38
NM_001322194.2 chr9:g.5090557C>A c.2873C>A p.S958Y RefSeq GRCh38/hg38
NM_001322195.1 chr9:g.5090557C>A c.2873C>A p.S958Y RefSeq GRCh38/hg38
NM_004972.3 chr9:g.5090557C>A c.2873C>A p.S958Y RefSeq GRCh38/hg38
NM_001322196.2 chr9:g.5090557C>A c.2873C>A p.S958Y RefSeq GRCh38/hg38
NM_001322195.2 chr9:g.5090557C>A c.2873C>A p.S958Y RefSeq GRCh38/hg38
NM_004972.4 chr9:g.5090557C>A c.2873C>A p.S958Y RefSeq GRCh38/hg38

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References