MSH6 K1014del
Gene Variant Detail

Request Content

Contact

Missing content? – Request curation!

Request curation for specific Genes, Variants, or PubMed publications.

Have questions, comments, or suggestions? - Let us know!

Email us at : ckbsupport@genomenon.com

Gene MSH6
Variant K1014del
Impact List deletion
Protein Effect unknown
Gene Variant Descriptions MSH6 K1014del results in the deletion of an amino acid in the lever domain of the Msh6 protein at amino acid 1014 (PMID: 17531815). K1014del has been identified in the scientific literature (PMID: 29875428, PMID: 36260514), but has not been biochemically characterized and therefore, its effect on Msh6 protein function is unknown (PubMed, Oct 2025).
Associated Drug Resistance
Category Variants Paths

MSH6 mutant MSH6 K1014del

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Transcript NM_000179.3
gDNA chr2:g.47801023_47801025delAAG
cDNA c.3040_3042delAAG
Protein p.K1014del
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_001406798.1 chr2:g.47801023_47801025delAAG c.3040_3042delAAG p.K1014delK RefSeq GRCh38/hg38
NM_001406796.1 chr2:g.47801023_47801025delAAG c.3040_3042delAAG p.K1014delK RefSeq GRCh38/hg38
NM_001406800.1 chr2:g.47801023_47801025delAAG c.3040_3042delAAG p.K1014delK RefSeq GRCh38/hg38
NM_001406808.1 chr2:g.47801023_47801025delAAG c.3040_3042delAAG p.K1014delK RefSeq GRCh38/hg38
NM_000179.3 chr2:g.47801023_47801025delAAG c.3040_3042delAAG p.K1014del RefSeq GRCh38/hg38
NM_000179.3 chr2:g.47801023_47801025delAAG c.3040_3042delAAG p.K1014delK RefSeq GRCh38/hg38

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References