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Gene TET2
Variant Q317fs
Impact List frameshift
Protein Effect loss of function - predicted
Gene Variant Descriptions TET2 Q317fs results in a change in the amino acid sequence of the Tet2 protein beginning at aa 317 of 2002, likely resulting in premature truncation of the functional protein (UniProt.org). Q317fs has not been characterized, however, due to the effects of other truncation mutations downstream of Q317 (PMID: 24994606), is predicted to lead to a loss of Tet2 protein function.
Associated Drug Resistance
Category Variants Paths

TET2 mutant TET2 inact mut TET2 Q317fs

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Transcript NM_001127208.3
gDNA chr4:g.(105234890_105234891)
cDNA c.(949_948)
Protein p.Q317fs
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
XM_024454103.2 chr4:g.(105234890_105234891) c.(949_948) p.Q317fs RefSeq GRCh38/hg38
NM_017628.4 chr4:g.(105234890_105234891) c.(949_948) p.Q317fs RefSeq GRCh38/hg38
XM_047415843.1 chr4:g.(105234890_105234891) c.(949_948) p.Q317fs RefSeq GRCh38/hg38
XM_024454102.1 chr4:g.(105234890_105234891) c.(949_948) p.Q317fs RefSeq GRCh38/hg38
XM_047415841.1 chr4:g.(105234890_105234891) c.(949_948) p.Q317fs RefSeq GRCh38/hg38
XM_017008319.2 chr4:g.(105234890_105234891) c.(949_948) p.Q317fs RefSeq GRCh38/hg38
XM_047415842.1 chr4:g.(105234890_105234891) c.(949_948) p.Q317fs RefSeq GRCh38/hg38
XM_017008319.1 chr4:g.(105234890_105234891) c.(949_948) p.Q317fs RefSeq GRCh38/hg38
NM_001127208.3 chr4:g.(105234890_105234891) c.(949_948) p.Q317fs RefSeq GRCh38/hg38
XM_005263082.4 chr4:g.(105234890_105234891) c.(949_948) p.Q317fs RefSeq GRCh38/hg38
XM_006714242.3 chr4:g.(105234890_105234891) c.(949_948) p.Q317fs RefSeq GRCh38/hg38
NM_001127208.2 chr4:g.(105234890_105234891) c.(949_948) p.Q317fs RefSeq GRCh38/hg38
XM_024454103.1 chr4:g.(105234890_105234891) c.(949_948) p.Q317fs RefSeq GRCh38/hg38
XM_047415839.1 chr4:g.(105234890_105234891) c.(949_948) p.Q317fs RefSeq GRCh38/hg38
XM_024454102.2 chr4:g.(105234890_105234891) c.(949_948) p.Q317fs RefSeq GRCh38/hg38
XM_006714242.4 chr4:g.(105234890_105234891) c.(949_948) p.Q317fs RefSeq GRCh38/hg38
XM_005263082.3 chr4:g.(105234890_105234891) c.(949_948) p.Q317fs RefSeq GRCh38/hg38
NM_017628.4 chr4:g.(105234890_105234891) c.(949_948) p.Q317fs RefSeq GRCh38/hg38
XM_047415840.1 chr4:g.(105234890_105234891) c.(949_948) p.Q317fs RefSeq GRCh38/hg38

Filtering

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  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

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  • Click on any column header arrows to sort by that column
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Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries