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Gene RAD51D
Variant A34V
Impact List missense
Protein Effect unknown
Gene Variant Descriptions RAD51D A34V lies within the region of the Rad51d protein that preferentially binds ssDNA (UniProt.org). A34V binds Xrcc2 at similar levels to wild-type Rad51d (PMID: 28864920), but has not been fully biochemically characterized and therefore, its effect on Rad51d protein function is unknown.
Associated Drug Resistance
Category Variants Paths

RAD51D mutant RAD51D A34V

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Transcript NM_002878.4
gDNA chr17:g.35119154G>A
cDNA c.101C>T
Protein p.A34V
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_001142571.2 chr17:g.35119154G>A c.101C>T p.A34V RefSeq GRCh38/hg38
NM_001142571.1 chr17:g.35119154G>A c.101C>T p.A34V RefSeq GRCh38/hg38
NM_002878.3 chr17:g.35119154G>A c.101C>T p.A34V RefSeq GRCh38/hg38
NM_133629.2 chr17:g.35119154G>A c.101C>T p.A34V RefSeq GRCh38/hg38
NM_002878.4 chr17:g.35119154G>A c.101C>T p.A34V RefSeq GRCh38/hg38
NM_133629.3 chr17:g.35119154G>A c.101C>T p.A34V RefSeq GRCh38/hg38

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

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  • Click on any column header arrows to sort by that column
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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References