CDK12 G1461C
Gene Variant Detail

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Gene CDK12
Variant G1461C
Impact List missense
Protein Effect unknown
Gene Variant Descriptions CDK12 G1461C does not lie within any known functional domains of the Cdk12 protein (UniProt.org). G1461C has not been characterized in the scientific literature and therefore, its effect on Cdk12 protein function is unknown (PubMed, Apr 2026).
Associated Drug Resistance
Category Variants Paths

CDK12 mutant CDK12 G1461C

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Transcript NM_016507.4
gDNA chr17:g.39531224G>T
cDNA c.4381G>T
Protein p.G1461C
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_016507.4 chr17:g.39531224G>T c.4381G>T p.G1461C RefSeq GRCh38/hg38
NM_016507.3 chr17:g.39531224G>T c.4381G>T p.G1461C RefSeq GRCh38/hg38

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Molecular Profile Protein Effect Treatment Approaches
CDK12 G1461C unknown