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Gene | RAD51C |
Variant | R237* |
Impact List | nonsense |
Protein Effect | unknown |
Gene Variant Descriptions | RAD51C R237* results in a premature truncation of the Rad51c protein at amino acid 237 of 376 (UniProt.org). R237* has been identified in the scientific literature (PMID: 37129948, PMID: 36451132), but has not been biochemically characterized and therefore, its effect on Rad51c protein function is unknown (PubMed, Oct 2024). |
Associated Drug Resistance | |
Category Variants Paths |
RAD51C mutant RAD51C R237* |
Transcript | NM_058216.3 |
gDNA | chr17:g.58709862C>T |
cDNA | c.709C>T |
Protein | p.R237* |
Source Database | RefSeq |
Genome Build | GRCh38/hg38 |
Transcript | gDNA | cDNA | Protein | Source Database | Genome Build |
---|---|---|---|---|---|
XM_006722002.4 | chr17:g.58709862C>T | c.709C>T | p.R237* | RefSeq | GRCh38/hg38 |
XM_006722002.5 | chr17:g.58709862C>T | c.709C>T | p.R237* | RefSeq | GRCh38/hg38 |
NM_058216.2 | chr17:g.58709862C>T | c.709C>T | p.R237* | RefSeq | GRCh38/hg38 |
NM_058216.3 | chr17:g.58709862C>T | c.709C>T | p.R237* | RefSeq | GRCh38/hg38 |
XM_006722001.4 | chr17:g.58709862C>T | c.709C>T | p.R237* | RefSeq | GRCh38/hg38 |
XM_006722001.5 | chr17:g.58709862C>T | c.709C>T | p.R237* | RefSeq | GRCh38/hg38 |
Molecular Profile | Protein Effect | Treatment Approaches |
---|---|---|
RAD51C R237* | unknown |