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Gene TP53
Variant T150_P151del
Impact List deletion
Protein Effect unknown
Gene Variant Descriptions TP53 T150_P151del results in the deletion of two amino acids in the CCAR2 and HRMT1L2-interacting regions of the Tp53 protein from amino acids 150 to 151 (UniProt.org). T150_P151del has not been characterized in the scientific literature and therefore, its effect on Tp53 protein function is unknown (PubMed, Feb 2024).
Associated Drug Resistance
Category Variants Paths

TP53 mutant TP53 exon5 TP53 T150_P151del

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Transcript NM_000546.6
gDNA chr17:g.7675161_7675166delGTGTGG
cDNA c.448_453delACACCC
Protein p.T150_P151del
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_001126112.2 chr17:g.7675161_7675166delGTGTGG c.448_453delACACCC p.T150_P151del RefSeq GRCh38/hg38
NM_001126113.2 chr17:g.7675161_7675166delGTGTGG c.448_453delACACCC p.T150_P151del RefSeq GRCh38/hg38
NM_001407262.1 chr17:g.7675161_7675166delGTGTGG c.448_453delACACCC p.T150_P151del RefSeq GRCh38/hg38
NM_001407266.1 chr17:g.7675161_7675166delGTGTGG c.448_453delACACCC p.T150_P151del RefSeq GRCh38/hg38
NM_001126114.2 chr17:g.7675161_7675166delGTGTGG c.448_453delACACCC p.T150_P151del RefSeq GRCh38/hg38
NM_001126113.3 chr17:g.7675161_7675166delGTGTGG c.448_453delACACCC p.T150_P151del RefSeq GRCh38/hg38
NM_001126114.3 chr17:g.7675161_7675166delGTGTGG c.448_453delACACCC p.T150_P151del RefSeq GRCh38/hg38
NM_000546.5 chr17:g.7675161_7675166delGTGTGG c.448_453delACACCC p.T150_P151del RefSeq GRCh38/hg38
NM_000546.6 chr17:g.7675161_7675166delGTGTGG c.448_453delACACCC p.T150_P151del RefSeq GRCh38/hg38
NM_001126112.3 chr17:g.7675161_7675166delGTGTGG c.448_453delACACCC p.T150_P151del RefSeq GRCh38/hg38
NM_001407268.1 chr17:g.7675161_7675166delGTGTGG c.448_453delACACCC p.T150_P151del RefSeq GRCh38/hg38
NM_001407270.1 chr17:g.7675161_7675166delGTGTGG c.448_453delACACCC p.T150_P151del RefSeq GRCh38/hg38
NM_001407264.1 chr17:g.7675161_7675166delGTGTGG c.448_453delACACCC p.T150_P151del RefSeq GRCh38/hg38

Filtering

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  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
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  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References