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Gene CDKN2A
Variant L63_P70del
Impact List deletion
Protein Effect unknown
Gene Variant Descriptions CDKN2A L63_P70del results in the deletion of eight amino acids in ANK repeat 2 of the Cdkn2a protein from amino acids 63 to 70 (UniProt.org). L63_P70del has not been characterized in the scientific literature and therefore, its effect on Cdkn2a protein function is unknown (PubMed, Oct 2024).
Associated Drug Resistance
Category Variants Paths

CDKN2A mutant CDKN2A L63_P70del

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Transcript NM_000077.5
gDNA chr9:g.21971149_21971172del24
cDNA c.187_210del24
Protein p.L63_P70del
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
XM_011517676.3 chr9:g.21971149_21971172del24 c.187_210del24 p.L63_P70del RefSeq GRCh38/hg38
XM_011517675.3 chr9:g.21971149_21971172del24 c.187_210del24 p.L63_P70del RefSeq GRCh38/hg38
NM_001195132.2 chr9:g.21971149_21971172del24 c.187_210del24 p.L63_P70del RefSeq GRCh38/hg38
NM_000077.5 chr9:g.21971149_21971172del24 c.187_210del24 p.L63_P70del RefSeq GRCh38/hg38

Filtering

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  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References