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Gene FBXW7
Variant R465G
Impact List missense
Protein Effect unknown
Gene Variant Descriptions FBXW7 R465G lies within WD repeat 3 of the Fbxw7 protein (UniProt.org). R465G has been identified in the scientific literature (PMID: 34817806), but has not been biochemically characterized and therefore, its effect on Fbxw7 protein function is unknown (PubMed, Jul 2024).
Associated Drug Resistance
Category Variants Paths

FBXW7 mutant FBXW7 R465G

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Transcript NM_033632.3
gDNA chr4:g.152328233G>C
cDNA c.1393C>G
Protein p.R465G
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
XM_011532084.3 chr4:g.152328233G>C c.1393C>G p.R465G RefSeq GRCh38/hg38
XM_047415899.1 chr4:g.152328233G>C c.1393C>G p.R465G RefSeq GRCh38/hg38
XM_047415898.1 chr4:g.152328233G>C c.1393C>G p.R465G RefSeq GRCh38/hg38
XM_011532085.3 chr4:g.152328233G>C c.1393C>G p.R465G RefSeq GRCh38/hg38
XM_047415901.1 chr4:g.152328233G>C c.1393C>G p.R465G RefSeq GRCh38/hg38
NM_001349798.2 chr4:g.152328233G>C c.1393C>G p.R465G RefSeq GRCh38/hg38
XM_024454123.2 chr4:g.152328233G>C c.1393C>G p.R465G RefSeq GRCh38/hg38
NM_033632.3 chr4:g.152328233G>C c.1393C>G p.R465G RefSeq GRCh38/hg38
XM_047415897.1 chr4:g.152328233G>C c.1393C>G p.R465G RefSeq GRCh38/hg38
XM_047415900.1 chr4:g.152328233G>C c.1393C>G p.R465G RefSeq GRCh38/hg38

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

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  • Click on any column header arrows to sort by that column
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Molecular Profile Protein Effect Treatment Approaches
FBXW7 R465G unknown