FGFR2 K569M
Gene Variant Detail

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Gene FGFR2
Variant K569M
Impact List missense
Protein Effect unknown
Gene Variant Descriptions FGFR2 K569M lies within the protein kinase domain of the Fgfr2 protein (UniProt.org). K569M has been identified in the scientific literature (PMID: 28034880), but has not been biochemically characterized and therefore, its effect on Fgfr2 protein function is unknown (PubMed, Nov 2025).
Associated Drug Resistance
Category Variants Paths

FGFR2 mutant FGFR2 K569M

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Transcript NM_000141.5
gDNA chr10:g.121496688_121496689delAAinsTG
cDNA c.1706_1707delAAinsTG
Protein p.K569M
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_000141.5 chr10:g.121496688_121496689delAAinsTG c.1706_1707delAAinsTG p.K569M RefSeq GRCh38/hg38

Filtering

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  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References