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Gene | CBL |
Variant | loss |
Impact List | unknown |
Protein Effect | loss of function |
Gene Variant Descriptions | CBL loss indicates loss of the CBL gene, mRNA, and protein. |
Associated Drug Resistance | |
Category Variants Paths |
CBL mutant CBL inact mut CBL loss |
Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
---|---|---|---|---|---|---|
NCT05849662 | Phase Ib/II | Azacitidine + Cytarabine + Fludarabine + Trametinib Azacitidine + Trametinib | A Phase I/II Study of Trametinib and Azacitidine for Patients With Newly Diagnosed Juvenile Myelomonocytic Leukemia | Recruiting | USA | 0 |