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Gene PIK3CA
Variant E453G
Impact List missense
Protein Effect unknown
Gene Variant Descriptions PIK3CA E453G lies within the C2 PI3K-type domain of the Pik3ca protein (UniProt.org). E453G has been identified in the scientific literature (PMID: 35768433), but has not been biochemically characterized and therefore, its effect on Pik3ca protein function is unknown (PubMed, Mar 2024).
Associated Drug Resistance
Category Variants Paths

PIK3CA mutant PIK3CA exon8 PIK3CA E453G

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Transcript NM_006218.4
gDNA chr3:g.179210292A>G
cDNA c.1358A>G
Protein p.E453G
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_006218 chr3:g.179210292A>G c.1358A>G p.E453G RefSeq GRCh38/hg38
XM_011512894.2 chr3:g.179210292A>G c.1358A>G p.E453G RefSeq GRCh38/hg38
XM_006713658.4 chr3:g.179210292A>G c.1358A>G p.E453G RefSeq GRCh38/hg38
NM_006218.4 chr3:g.179210292A>G c.1358A>G p.E453G RefSeq GRCh38/hg38
XM_006713658 chr3:g.179210292A>G c.1358A>G p.E453G RefSeq GRCh38/hg38
XM_011512894 chr3:g.179210292A>G c.1358A>G p.E453G RefSeq GRCh38/hg38
NM_006218.3 chr3:g.179210292A>G c.1358A>G p.E453G RefSeq GRCh38/hg38
XM_006713658.5 chr3:g.179210292A>G c.1358A>G p.E453G RefSeq GRCh38/hg38

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

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Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries