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Gene TET2
Variant C784fs
Impact List frameshift
Protein Effect loss of function - predicted
Gene Variant Descriptions TET2 C784fs results in a change in the amino acid sequence of the Tet2 protein beginning at aa 784 of 2002, likely resulting in premature truncation of the functional protein (UniProt.org). C784fs has not been characterized however, due to the effects of other truncation mutations downstream of C784 (PMID: 24994606), is predicted to lead to a loss of Tet2 protein function.
Associated Drug Resistance
Category Variants Paths

TET2 mutant TET2 inact mut TET2 C784fs

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Transcript NM_001127208.3
gDNA chr4:g.(105236291_105236292)
cDNA c.(2350_2349)
Protein p.C784fs
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_017628.4 chr4:g.(105236291_105236292) c.(2350_2349) p.C784fs RefSeq GRCh38/hg38
NM_001127208.3 chr4:g.(105236291_105236292) c.(2350_2349) p.C784fs RefSeq GRCh38/hg38
XM_006714242.4 chr4:g.(105236291_105236292) c.(2350_2349) p.C784fs RefSeq GRCh38/hg38
XM_005263082.4 chr4:g.(105236291_105236292) c.(2350_2349) p.C784fs RefSeq GRCh38/hg38
XM_017008319.2 chr4:g.(105236291_105236292) c.(2350_2349) p.C784fs RefSeq GRCh38/hg38
XM_047415841.1 chr4:g.(105236291_105236292) c.(2350_2349) p.C784fs RefSeq GRCh38/hg38
XM_047415843.1 chr4:g.(105236291_105236292) c.(2350_2349) p.C784fs RefSeq GRCh38/hg38
XM_047415839.1 chr4:g.(105236291_105236292) c.(2350_2349) p.C784fs RefSeq GRCh38/hg38
XM_024454102.2 chr4:g.(105236291_105236292) c.(2350_2349) p.C784fs RefSeq GRCh38/hg38
XM_047415840.1 chr4:g.(105236291_105236292) c.(2350_2349) p.C784fs RefSeq GRCh38/hg38
XM_047415842.1 chr4:g.(105236291_105236292) c.(2350_2349) p.C784fs RefSeq GRCh38/hg38
XM_024454103.2 chr4:g.(105236291_105236292) c.(2350_2349) p.C784fs RefSeq GRCh38/hg38

Filtering

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  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

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  • Click on any column header arrows to sort by that column
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Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries