FGFR2 K527E
Gene Variant Detail

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Gene FGFR2
Variant K527E
Impact List missense
Protein Effect unknown
Gene Variant Descriptions FGFR2 K527E (corresponds to K526E in the canonical isoform) lies within the protein kinase domain of the Fgfr2 protein (UniProt.org). K527E has been identified in the scientific literature (PMID: 39226398), but has not been biochemically characterized and therefore, its effect on Fgfr2 protein function is unknown (PubMed, Nov 2025).
Associated Drug Resistance
Category Variants Paths

FGFR2 mutant FGFR2 K527E

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Transcript NM_001144913.1
gDNA chr10:g.121498591T>C
cDNA c.1579A>G
Protein p.K527E
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_001144913.1 chr10:g.121498591T>C c.1579A>G p.K527E RefSeq GRCh38/hg38
NM_022970.4 chr10:g.121498591T>C c.1579A>G p.K527E RefSeq GRCh38/hg38

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

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  • Click on any column header arrows to sort by that column
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Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries