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| Gene | CBL |
| Variant | LOH |
| Impact List | deletion |
| Protein Effect | unknown |
| Gene Variant Descriptions | CBL LOH indicates the loss of one parental copy of the CBL gene, resulting in loss of heterozygosity. |
| Associated Drug Resistance | |
| Category Variants Paths |
CBL LOH |
| Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
|---|---|---|---|---|---|---|
| NCT05849662 | Phase Ib/II | Azacitidine + Cytarabine + Fludarabine + Trametinib Azacitidine + Trametinib | A Phase I/II Study of Trametinib and Azacitidine for Patients With Newly Diagnosed Juvenile Myelomonocytic Leukemia | Recruiting | USA | 0 |