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Gene | IDH2 |
Variant | act mut |
Impact List | unknown |
Protein Effect | gain of function |
Gene Variant Descriptions | IDH2 act mut indicates that this variant results in a gain of function in the Idh2 protein. However, the specific amino acid change has not been identified. |
Associated Drug Resistance | |
Category Variants Paths |
IDH2 mutant IDH2 act mut |
Molecular Profile | Protein Effect | Treatment Approaches |
---|---|---|
IDH2 act mut | gain of function | IDH Inhibitor (Pan) IDH2 Inhibitor |