TP53 L265_G266del
Gene Variant Detail

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Gene TP53
Variant L265_G266del
Impact List deletion
Protein Effect unknown
Gene Variant Descriptions TP53 L265_G266del results in the deletion of two amino acids in the DNA-binding domain of the Tp53 protein from amino acids 265 to 266 (UniProt.org). L265_G266del has been identified in the scientific literature (PMID: 41504628), but has not been biochemically characterized and therefore, its effect on Tp53 protein function is unknown (PubMed, Apr 2026).
Associated Drug Resistance
Category Variants Paths

TP53 mutant TP53 exon8 TP53 L265_G266del

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Transcript NM_000546.6
gDNA chr17:g.7673823_7673828delCCCAGT
cDNA c.794_799delTGGGAC
Protein p.L265_G266del
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_000546.6 chr17:g.7673823_7673828delCCCAGT c.794_799delTGGGAC p.L265_G266del RefSeq GRCh38/hg38

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  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

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Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries