RAD51C S364G
Gene Variant Detail

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Gene RAD51C
Variant S364G
Impact List missense
Protein Effect no effect - predicted
Gene Variant Descriptions RAD51C S364G does not lie within any known functional domains of the Rad51c protein (UniProt.org). S364G retains binding to Rad51d similar to wild-type Rad51c in a yeast assay, and demonstrates functional homology-directed DNA repair activity in culture (PMID: 40670332, PMID: 37253112), and therefore is predicted to have no effect on Rad51c protein function.
Associated Drug Resistance
Category Variants Paths

RAD51C mutant RAD51C S364G

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Transcript NM_058216.3
gDNA chr17:g.58734181A>G
cDNA c.1090A>G
Protein p.S364G
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_058216.3 chr17:g.58734181A>G c.1090A>G p.S364G RefSeq GRCh38/hg38

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References