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Gene FBXW7
Variant G411S
Impact List missense
Protein Effect unknown
Gene Variant Descriptions FBXW7 G411S lies within WD repeat 1 of the Fbxw7 protein (UniProt.org). G411S has not been characterized in the scientific literature and therefore, its effect on Fbxw7 protein function is unknown (PubMed, Oct 2024).
Associated Drug Resistance
Category Variants Paths

FBXW7 mutant FBXW7 G411S

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Transcript NM_033632.3
gDNA chr4:g.152329677C>T
cDNA c.1231G>A
Protein p.G411S
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_033632.3 chr4:g.152329677C>T c.1231G>A p.G411S RefSeq GRCh38/hg38
XM_024454123.1 chr4:g.152329677C>T c.1231G>A p.G411S RefSeq GRCh38/hg38
XM_011532084.3 chr4:g.152329677C>T c.1231G>A p.G411S RefSeq GRCh38/hg38
XM_024454124.1 chr4:g.152329677C>T c.1231G>A p.G411S RefSeq GRCh38/hg38
XM_047415900.1 chr4:g.152329677C>T c.1231G>A p.G411S RefSeq GRCh38/hg38
XM_047415898.1 chr4:g.152329677C>T c.1231G>A p.G411S RefSeq GRCh38/hg38
XM_011532084.2 chr4:g.152329677C>T c.1231G>A p.G411S RefSeq GRCh38/hg38
XM_024454123.2 chr4:g.152329677C>T c.1231G>A p.G411S RefSeq GRCh38/hg38
NM_033632 chr4:g.152329677C>T c.1231G>A p.G411S RefSeq GRCh38/hg38
XM_024454121.1 chr4:g.152329677C>T c.1231G>A p.G411S RefSeq GRCh38/hg38
NM_018315 chr4:g.152326179C>T c.1231G>A p.G411S RefSeq GRCh38/hg38
XM_047415897.1 chr4:g.152329677C>T c.1231G>A p.G411S RefSeq GRCh38/hg38
XM_011532084 chr4:g.152329677C>T c.1231G>A p.G411S RefSeq GRCh38/hg38
XM_047415899.1 chr4:g.152329677C>T c.1231G>A p.G411S RefSeq GRCh38/hg38
XM_047415901.1 chr4:g.152329677C>T c.1231G>A p.G411S RefSeq GRCh38/hg38
NM_018315.5 chr4:g.152326179C>T c.1231G>A p.G411S RefSeq GRCh38/hg38
NM_018315.4 chr4:g.152326179C>T c.1231G>A p.G411S RefSeq GRCh38/hg38
XM_011532083 chr4:g.152329677C>T c.1231G>A p.G411S RefSeq GRCh38/hg38
NM_033632.3 chr4:g.152329677C>T c.1231G>A p.G411S RefSeq GRCh38/hg38
NM_001349798.1 chr4:g.152329677C>T c.1231G>A p.G411S RefSeq GRCh38/hg38
XM_011532085 chr4:g.152329677C>T c.1231G>A p.G411S RefSeq GRCh38/hg38
XM_011532085.2 chr4:g.152329677C>T c.1231G>A p.G411S RefSeq GRCh38/hg38
XM_017008362 chr4:g.152329677C>T c.1231G>A p.G411S RefSeq GRCh38/hg38
XM_024454122.1 chr4:g.152329677C>T c.1231G>A p.G411S RefSeq GRCh38/hg38
XM_011532085.3 chr4:g.152329677C>T c.1231G>A p.G411S RefSeq GRCh38/hg38
NM_001349798.2 chr4:g.152329677C>T c.1231G>A p.G411S RefSeq GRCh38/hg38

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References