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Gene | FBXW7 |
Variant | G579W |
Impact List | missense |
Protein Effect | unknown |
Gene Variant Descriptions | FBXW7 G579W does not lie within any known functional domains of the Fbxw7 protein (UniProt.org). G579W has been identified in the scientific literature (PMID: 24755471, PMID: 27399335), but has not been biochemically characterized and therefore, its effect on Fbxw7 protein function is unknown (PubMed, Apr 2025). |
Associated Drug Resistance | |
Category Variants Paths |
FBXW7 mutant FBXW7 G579W |
Transcript | NM_001349798.2 |
gDNA | chr4:g.152324304C>A |
cDNA | c.1735G>T |
Protein | p.G579W |
Source Database | RefSeq |
Genome Build | GRCh38/hg38 |