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Gene | FBXW7 |
Variant | H382N |
Impact List | missense |
Protein Effect | unknown |
Gene Variant Descriptions | FBXW7 H382N lies within WD repeat 1 of the Fbxw7 protein (UniProt.org). H382N has been identified in sequencing studies (PMID: 26010451), but has not been biochemically characterized and therefore, its effect on Fbxw7 protein function is unknown (PubMed, Apr 2025). |
Associated Drug Resistance | |
Category Variants Paths |
FBXW7 mutant FBXW7 H382N |
Transcript | NM_033632.3 |
gDNA | chr4:g.152329764G>T |
cDNA | c.1144C>A |
Protein | p.H382N |
Source Database | RefSeq |
Genome Build | GRCh38/hg38 |