SRC P506L
Gene Variant Detail

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Gene SRC
Variant P506L
Impact List missense
Protein Effect unknown
Gene Variant Descriptions SRC P506L lies within the protein kinase domain of the Src protein (UniProt.org). P506L has been identified in sequencing studies (PMID: 24265154), but has not been biochemically characterized and therefore, its effect on Src protein function is unknown (PubMed, Mar 2026).
Associated Drug Resistance
Category Variants Paths

SRC mutant SRC P506L

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Transcript NM_198291.3
gDNA chr20:g.37403285C>T
cDNA c.1517C>T
Protein p.P506L
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_005417 chr20:g.37403285C>T c.1517C>T p.P506L RefSeq GRCh38/hg38
NM_198291.3 chr20:g.37403285C>T c.1517C>T p.P506L RefSeq GRCh38/hg38
XM_047440405.1 chr20:g.37403285C>T c.1517C>T p.P506L RefSeq GRCh38/hg38
XM_047440413.1 chr20:g.37403285C>T c.1517C>T p.P506L RefSeq GRCh38/hg38
XM_047440411.1 chr20:g.37403285C>T c.1517C>T p.P506L RefSeq GRCh38/hg38
XM_047440401.1 chr20:g.37403285C>T c.1517C>T p.P506L RefSeq GRCh38/hg38
NM_005417.4 chr20:g.37403285C>T c.1517C>T p.P506L RefSeq GRCh38/hg38
XM_047440402.1 chr20:g.37403285C>T c.1517C>T p.P506L RefSeq GRCh38/hg38
XM_047440406.1 chr20:g.37403285C>T c.1517C>T p.P506L RefSeq GRCh38/hg38
NM_198291.2 chr20:g.37403285C>T c.1517C>T p.P506L RefSeq GRCh38/hg38
NM_005417.5 chr20:g.37403285C>T c.1517C>T p.P506L RefSeq GRCh38/hg38
NM_198291 chr20:g.37403285C>T c.1517C>T p.P506L RefSeq GRCh38/hg38
XM_011529013.2 chr20:g.37403285C>T c.1517C>T p.P506L RefSeq GRCh38/hg38
XM_047440403.1 chr20:g.37403285C>T c.1517C>T p.P506L RefSeq GRCh38/hg38
XM_047440410.1 chr20:g.37403285C>T c.1517C>T p.P506L RefSeq GRCh38/hg38
XM_047440404.1 chr20:g.37403285C>T c.1517C>T p.P506L RefSeq GRCh38/hg38
XM_011529013 chr20:g.37403285C>T c.1517C>T p.P506L RefSeq GRCh38/hg38
XM_047440412.1 chr20:g.37403285C>T c.1517C>T p.P506L RefSeq GRCh38/hg38

Filtering

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  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References