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| Gene | TP53 |
| Variant | loss |
| Impact List | unknown |
| Protein Effect | loss of function |
| Gene Variant Descriptions | TP53 loss indicates loss of the TP53 gene, mRNA, and protein. |
| Associated Drug Resistance | |
| Category Variants Paths |
TP53 mutant TP53 inact mut TP53 loss |
| Molecular Profile | Protein Effect | Treatment Approaches |
|---|---|---|
| TP53 loss | loss of function | |
| ALK rearrange RB1 C706F TP53 loss | ||
| PTEN loss TP53 loss | ||
| TP53 loss TP53 mut |