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Gene IDH1
Variant D375Y
Impact List missense
Protein Effect unknown
Gene Variant Descriptions IDH1 D375Y does not lie within any known functional domains of the Idh1 protein (UniProt.org). D375Y has been identified in the scientific literature (PMID: 32313423), but has not been biochemically characterized and therefore, its effect on Idh1 protein function is unknown (PubMed, Oct 2024).
Associated Drug Resistance
Category Variants Paths

IDH1 mutant IDH1 D375Y

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Transcript NM_005896.4
gDNA chr2:g.208239102C>A
cDNA c.1123G>T
Protein p.D375Y
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_005896.4 chr2:g.208239102C>A c.1123G>T p.D375Y RefSeq GRCh38/hg38
NM_005896.3 chr2:g.208239102C>A c.1123G>T p.D375Y RefSeq GRCh38/hg38
NM_005896 chr2:g.208239102C>A c.1123G>T p.D375Y RefSeq GRCh38/hg38
NM_001282386.1 chr2:g.208239102C>A c.1123G>T p.D375Y RefSeq GRCh38/hg38
NM_001282386 chr2:g.208239102C>A c.1123G>T p.D375Y RefSeq GRCh38/hg38
NM_001282387 chr2:g.208239102C>A c.1123G>T p.D375Y RefSeq GRCh38/hg38
NM_001282387.1 chr2:g.208239102C>A c.1123G>T p.D375Y RefSeq GRCh38/hg38
NM_001282386.1 chr2:g.208239102C>A c.1123G>T p.D375Y RefSeq GRCh38/hg38
NM_001282387.1 chr2:g.208239102C>A c.1123G>T p.D375Y RefSeq GRCh38/hg38

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

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Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries