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Gene KIT
Variant L859F
Impact List missense
Protein Effect unknown
Gene Variant Descriptions KIT L859F lies within the protein kinase domain of the Kit protein (UniProt.org). L859F has not been characterized in the scientific literature and therefore, its effect on Kit protein function is unknown (PubMed, Nov 2024).
Associated Drug Resistance
Category Variants Paths

KIT mutant KIT exon18 KIT L859F

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Transcript NM_000222.3
gDNA chr4:g.54736588C>T
cDNA c.2575C>T
Protein p.L859F
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
XM_005265741.1 chr4:g.54736588C>T c.2575C>T p.L859F RefSeq GRCh38/hg38
NM_000222 chr4:g.54736588C>T c.2575C>T p.L859F RefSeq GRCh38/hg38
NM_000222.2 chr4:g.54736588C>T c.2575C>T p.L859F RefSeq GRCh38/hg38
NM_000222.3 chr4:g.54736588C>T c.2575C>T p.L859F RefSeq GRCh38/hg38
XM_005265742.3 chr4:g.54736597_54736599delCTGinsTTT c.2575_2577delCTGinsTTT p.L859F RefSeq GRCh38/hg38
NM_001385290.1 chr4:g.54736588C>T c.2575C>T p.L859F RefSeq GRCh38/hg38
NM_001385288.1 chr4:g.54736597_54736599delCTGinsTTT c.2575_2577delCTGinsTTT p.L859F RefSeq GRCh38/hg38
XM_005265741 chr4:g.54736588C>T c.2575C>T p.L859F RefSeq GRCh38/hg38
XM_005265742 chr4:g.54736597_54736599delCTGinsTTT c.2575_2577delCTGinsTTT p.L859F RefSeq GRCh38/hg38

Filtering

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  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

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Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries