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Gene FLT3
Variant D895Y
Impact List missense
Protein Effect unknown
Gene Variant Descriptions FLT3 D895Y lies within the protein kinase domain of the Flt3 protein (UniProt.org). D895Y has been identified in sequencing studies (PMID: 22810696), but has not been biochemically characterized and therefore, its effect on Flt3 protein function is unknown (PubMed, Apr 2024).
Associated Drug Resistance
Category Variants Paths

FLT3 mutant FLT3 exon22 FLT3 D895Y

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Transcript NM_004119.3
gDNA chr13:g.28015227C>A
cDNA c.2683G>T
Protein p.D895Y
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_004119.2 chr13:g.28015227C>A c.2683G>T p.D895Y RefSeq GRCh38/hg38
NM_004119 chr13:g.28015227C>A c.2683G>T p.D895Y RefSeq GRCh38/hg38
NM_004119.3 chr13:g.28015227C>A c.2683G>T p.D895Y RefSeq GRCh38/hg38

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References