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Gene APC
Variant V1822D
Impact List missense
Protein Effect unknown
Gene Variant Descriptions APC V1822D lies within the beta-catenin binding and downregulation region of the Apc protein (PMID: 14672538). V1822D is a common Apc polymorphism (PMID: 11584047, PMID: 16569251, PMID: 11221825), but has not been biochemically characterized and therefore, its effect on Apc protein function is unknown (PubMed, Aug 2024).
Associated Drug Resistance
Category Variants Paths

APC mutant APC V1822D

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Transcript NM_000038.6
gDNA chr5:g.112841059T>A
cDNA c.5465T>A
Protein p.V1822D
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_000038.6 chr5:g.112841059T>A c.5465T>A p.V1822D RefSeq GRCh38/hg38
NM_001354896.1 chr5:g.112841005T>A c.5465T>A p.V1822D RefSeq GRCh38/hg38
NM_001354895.2 chr5:g.112841059T>A c.5465T>A p.V1822D RefSeq GRCh38/hg38
NM_001407447.1 chr5:g.112841005T>A c.5465T>A p.V1822D RefSeq GRCh38/hg38
NM_001127510.3 chr5:g.112841059T>A c.5465T>A p.V1822D RefSeq GRCh38/hg38
NM_000038 chr5:g.112841059T>A c.5465T>A p.V1822D RefSeq GRCh38/hg38
NM_001407448.1 chr5:g.112841005T>A c.5465T>A p.V1822D RefSeq GRCh38/hg38
NM_001407449.1 chr5:g.112841005T>A c.5465T>A p.V1822D RefSeq GRCh38/hg38
NM_000038.5 chr5:g.112841059T>A c.5465T>A p.V1822D RefSeq GRCh38/hg38
NM_001127510.2 chr5:g.112841059T>A c.5465T>A p.V1822D RefSeq GRCh38/hg38
NM_001127510 chr5:g.112841059T>A c.5465T>A p.V1822D RefSeq GRCh38/hg38
NM_001407450.1 chr5:g.112841059T>A c.5465T>A p.V1822D RefSeq GRCh38/hg38
NM_001354895.1 chr5:g.112841059T>A c.5465T>A p.V1822D RefSeq GRCh38/hg38
NM_001354896.2 chr5:g.112841005T>A c.5465T>A p.V1822D RefSeq GRCh38/hg38

Filtering

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  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
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  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

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  • Click on any column header arrows to sort by that column
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Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries