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| Gene | ERBB3 |
| Variant | T355A |
| Impact List | missense |
| Protein Effect | unknown |
| Gene Variant Descriptions | ERBB3 (HER3) T355A lies within the extracellular domain of the Erbb3 (Her3) protein (UniProt.org). T355A has been identified in the scientific literature (PMID: 29338072, PMID: 29967250, PMID: 29420467), but has not been biochemically characterized and therefore, its effect on Erbb3 (Her3) protein function is unknown (PubMed, Jan 2026). |
| Associated Drug Resistance | |
| Category Variants Paths |
ERBB3 mutant ERBB3 T355A |
| Transcript | NM_001982.4 |
| gDNA | chr12:g.56088822A>G |
| cDNA | c.1063A>G |
| Protein | p.T355A |
| Source Database | RefSeq |
| Genome Build | GRCh38/hg38 |
| Transcript | gDNA | cDNA | Protein | Source Database | Genome Build |
|---|---|---|---|---|---|
| NM_001982.3 | chr12:g.56088822A>G | c.1063A>G | p.T355A | RefSeq | GRCh38/hg38 |
| NM_001982 | chr12:g.56088822A>G | c.1063A>G | p.T355A | RefSeq | GRCh38/hg38 |
| NM_001982.4 | chr12:g.56088822A>G | c.1063A>G | p.T355A | RefSeq | GRCh38/hg38 |
| Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
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