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Gene IDH2
Variant E68K
Impact List missense
Protein Effect unknown
Gene Variant Descriptions IDH2 E68K does not lie within any known functional domains of the Idh2 protein (UniProt.org). E68K has not been characterized in the scientific literature and therefore, its effect on Idh2 protein function is unknown (PubMed, Apr 2024).
Associated Drug Resistance
Category Variants Paths

IDH2 mutant IDH2 E68K

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Transcript NM_002168.4
gDNA chr15:g.90091558C>T
cDNA c.202G>A
Protein p.E68K
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_001289910 chr15:g.90090494C>T c.202G>A p.E68K RefSeq GRCh38/hg38
NM_001289910.1 chr15:g.90090494C>T c.202G>A p.E68K RefSeq GRCh38/hg38
NM_001289910.1 chr15:g.90090494C>T c.202G>A p.E68K RefSeq GRCh38/hg38
NM_002168.4 chr15:g.90091558C>T c.202G>A p.E68K RefSeq GRCh38/hg38
NM_002168 chr15:g.90091558C>T c.202G>A p.E68K RefSeq GRCh38/hg38
NM_002168.3 chr15:g.90091558C>T c.202G>A p.E68K RefSeq GRCh38/hg38

Filtering

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  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References