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Gene FLT3
Variant K290T
Impact List missense
Protein Effect unknown
Gene Variant Descriptions FLT3 K290T lies within the Ig-like C2-type domain of the Flt3 protein (UniProt.org). K290T has not been characterized in the scientific literature and therefore, its effect on Flt3 protein function is unknown (PubMed, Apr 2024).
Associated Drug Resistance
Category Variants Paths

FLT3 mutant FLT3 K290T

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Transcript NM_004119.3
gDNA chr13:g.28049648T>G
cDNA c.869A>C
Protein p.K290T
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_004119.3 chr13:g.28049648T>G c.869A>C p.K290T RefSeq GRCh38/hg38
XM_017020487.1 chr13:g.28035959T>G c.869A>C p.K290T RefSeq GRCh38/hg38
NM_004119 chr13:g.28049648T>G c.869A>C p.K290T RefSeq GRCh38/hg38
XM_011535017.2 chr13:g.28035959T>G c.869A>C p.K290T RefSeq GRCh38/hg38
XM_017020487 chr13:g.28035959T>G c.869A>C p.K290T RefSeq GRCh38/hg38
XM_011535018.2 chr13:g.28035959T>G c.869A>C p.K290T RefSeq GRCh38/hg38
XM_011535018.3 chr13:g.28035959T>G c.869A>C p.K290T RefSeq GRCh38/hg38
XM_011535017 chr13:g.28035959T>G c.869A>C p.K290T RefSeq GRCh38/hg38
XM_011535018 chr13:g.28035959T>G c.869A>C p.K290T RefSeq GRCh38/hg38
NM_004119.2 chr13:g.28049648T>G c.869A>C p.K290T RefSeq GRCh38/hg38
XM_047430216.1 chr13:g.28035959T>G c.869A>C p.K290T RefSeq GRCh38/hg38

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References