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Gene | FLT3 |
Variant | P986L |
Impact List | missense |
Protein Effect | unknown |
Gene Variant Descriptions | FLT3 P986L lies within the cytoplasmic domain of the Flt3 protein (UniProt.org). P986L has not been characterized in the scientific literature and therefore, its effect on Flt3 protein function is unknown (PubMed, Dec 2023). |
Associated Drug Resistance | |
Category Variants Paths |
FLT3 mutant FLT3 P986L |
Transcript | NM_004119.3 |
gDNA | chr13:g.28004077G>A |
cDNA | c.2957C>T |
Protein | p.P986L |
Source Database | RefSeq |
Genome Build | GRCh38/hg38 |
Transcript | gDNA | cDNA | Protein | Source Database | Genome Build |
---|---|---|---|---|---|
NM_004119.2 | chr13:g.28004077G>A | c.2957C>T | p.P986L | RefSeq | GRCh38/hg38 |
NM_004119.3 | chr13:g.28004077G>A | c.2957C>T | p.P986L | RefSeq | GRCh38/hg38 |
NM_004119 | chr13:g.28004077G>A | c.2957C>T | p.P986L | RefSeq | GRCh38/hg38 |
Molecular Profile | Protein Effect | Treatment Approaches |
---|---|---|
FLT3 P986L | unknown |