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Gene | FLT3 |
Variant | V843A |
Impact List | missense |
Protein Effect | unknown |
Gene Variant Descriptions | FLT3 V843A lies within the protein kinase domain of the Flt3 protein (UniProt.org). V843A has not been characterized in the scientific literature and therefore, its effect on Flt3 protein function is unknown (PubMed, May 2024). |
Associated Drug Resistance | |
Category Variants Paths |
FLT3 mutant FLT3 exon20 FLT3 V843A |
Transcript | NM_004119.3 |
gDNA | chr13:g.28018480A>G |
cDNA | c.2528T>C |
Protein | p.V843A |
Source Database | RefSeq |
Genome Build | GRCh38/hg38 |
Transcript | gDNA | cDNA | Protein | Source Database | Genome Build |
---|---|---|---|---|---|
NM_004119.3 | chr13:g.28018480A>G | c.2528T>C | p.V843A | RefSeq | GRCh38/hg38 |
NM_004119 | chr13:g.28018480A>G | c.2528T>C | p.V843A | RefSeq | GRCh38/hg38 |
NM_004119.2 | chr13:g.28018480A>G | c.2528T>C | p.V843A | RefSeq | GRCh38/hg38 |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
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