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Gene | TP53 |
Variant | over exp |
Impact List | none |
Protein Effect | no effect |
Gene Variant Descriptions | TP53 over exp indicates an over expression of the Tp53 protein. However, the mechanism causing the over expression is unspecified. |
Associated Drug Resistance | |
Category Variants Paths |
Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
---|---|---|---|---|---|---|
NCT02432963 | Phase I | MVAp53 + Pembrolizumab | Vaccine Therapy and Pembrolizumab in Treating Patients With Solid Tumors That Have Failed Prior Therapy | Active, not recruiting | USA | 0 |
NCT06482684 | Phase II | Ibrutinib Ibrutinib + Rituximab Bendamustine + Ibrutinib + Rituximab Cyclophosphamide + Doxorubicin + Ibrutinib + Prednisone + Rituximab + Vincristine Sulfate Brexucabtagene autoleucel Cisplatin + Cytarabine + Dexamethasone + Rituximab | CAR-T-cell Treatment for Untreated High Risk MANtle Cell Lymphoma (CARMAN) | Recruiting | DEU | 0 |