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Gene CHEK2
Variant S24C
Impact List missense
Protein Effect unknown
Gene Variant Descriptions CHEK2 S24C does not lie within any known functional domains of the Chek2 protein (UniProt.org). S24C has not been characterized in the scientific literature and therefore, its effect on Chek2 protein function is unknown (PubMed, Sep 2024).
Associated Drug Resistance
Category Variants Paths

CHEK2 mutant CHEK2 S24C

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Transcript NM_007194.4
gDNA chr22:g.28734652T>A
cDNA c.70A>T
Protein p.S24C
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_007194.3 chr22:g.28734652T>A c.70A>T p.S24C RefSeq GRCh38/hg38
NM_001005735.1 chr22:g.28734652T>A c.70A>T p.S24C RefSeq GRCh38/hg38
NM_001005735.2 chr22:g.28734652T>A c.70A>T p.S24C RefSeq GRCh38/hg38
NM_001005735 chr22:g.28734652T>A c.70A>T p.S24C RefSeq GRCh38/hg38
XM_011529843 chr22:g.28734652T>A c.70A>T p.S24C RefSeq GRCh38/hg38
XM_047441104.1 chr22:g.28734652T>A c.70A>T p.S24C RefSeq GRCh38/hg38
XM_047441105.1 chr22:g.28734652T>A c.70A>T p.S24C RefSeq GRCh38/hg38
XM_011529841 chr22:g.28734652T>A c.70A>T p.S24C RefSeq GRCh38/hg38
NM_145862.2 chr22:g.28734652T>A c.70A>T p.S24C RefSeq GRCh38/hg38
XM_047441106.1 chr22:g.28734652T>A c.70A>T p.S24C RefSeq GRCh38/hg38
NM_145862.2 chr22:g.28734652T>A c.70A>T p.S24C RefSeq GRCh38/hg38
XM_011529841.1 chr22:g.28734652T>A c.70A>T p.S24C RefSeq GRCh38/hg38
NM_007194.4 chr22:g.28734652T>A c.70A>T p.S24C RefSeq GRCh38/hg38
NM_145862 chr22:g.28734652T>A c.70A>T p.S24C RefSeq GRCh38/hg38
NM_001349956.1 chr22:g.28734652T>A c.70A>T p.S24C RefSeq GRCh38/hg38
NM_007194 chr22:g.28734652T>A c.70A>T p.S24C RefSeq GRCh38/hg38
NM_001349956.2 chr22:g.28734652T>A c.70A>T p.S24C RefSeq GRCh38/hg38

Filtering

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  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

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  • Click on any column header arrows to sort by that column
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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References