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Gene | FLT3 |
Variant | I836M |
Impact List | missense |
Protein Effect | unknown |
Gene Variant Descriptions | FLT3 I836M lies within the protein kinase domain of the Flt3 protein (UniProt.org). I836M has been identified in the scientific literature (PMID: 15390271, PMID: 15674414, PMID: 38542393), but has not been biochemically characterized and therefore, its effect on Flt3 protein function is unknown (PubMed, May 2024). |
Associated Drug Resistance | |
Category Variants Paths |
FLT3 mutant FLT3 exon20 FLT3 I836X FLT3 I836M |
Transcript | NM_004119.3 |
gDNA | chr13:g.28018500G>C |
cDNA | c.2508C>G |
Protein | p.I836M |
Source Database | RefSeq |
Genome Build | GRCh38/hg38 |
Transcript | gDNA | cDNA | Protein | Source Database | Genome Build |
---|---|---|---|---|---|
NM_004119 | chr13:g.28018500G>C | c.2508C>G | p.I836M | RefSeq | GRCh38/hg38 |
NM_004119.2 | chr13:g.28018500G>C | c.2508C>G | p.I836M | RefSeq | GRCh38/hg38 |
NM_004119.3 | chr13:g.28018500G>C | c.2508C>G | p.I836M | RefSeq | GRCh38/hg38 |
Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
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