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Gene JAK2
Variant F439S
Impact List missense
Protein Effect unknown
Gene Variant Descriptions JAK2 F439S lies within the atypical SH2 domain of the Jak2 protein (UniProt.org). F439S has not been characterized and therefore, its effect on Jak2 protein function is unknown (PubMed, May 2024).
Associated Drug Resistance
Category Variants Paths

JAK2 mutant JAK2 F439S

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Transcript NM_004972.4
gDNA chr9:g.5066779T>C
cDNA c.1316T>C
Protein p.F439S
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_001322196 chr9:g.5066779T>C c.1316T>C p.F439S RefSeq GRCh38/hg38
NM_001322194.1 chr9:g.5066779T>C c.1316T>C p.F439S RefSeq GRCh38/hg38
NM_001322196.1 chr9:g.5066779T>C c.1316T>C p.F439S RefSeq GRCh38/hg38
NM_001322198.2 chr9:g.5081821T>C c.1316T>C p.F439S RefSeq GRCh38/hg38
NM_001322198.1 chr9:g.5081821T>C c.1316T>C p.F439S RefSeq GRCh38/hg38
NM_001322195.2 chr9:g.5066779T>C c.1316T>C p.F439S RefSeq GRCh38/hg38
NM_001322194.2 chr9:g.5066779T>C c.1316T>C p.F439S RefSeq GRCh38/hg38
NM_001322196.2 chr9:g.5066779T>C c.1316T>C p.F439S RefSeq GRCh38/hg38
NM_001322195.1 chr9:g.5066779T>C c.1316T>C p.F439S RefSeq GRCh38/hg38
NM_001322199.2 chr9:g.5081821T>C c.1316T>C p.F439S RefSeq GRCh38/hg38
NM_001322194 chr9:g.5066779T>C c.1316T>C p.F439S RefSeq GRCh38/hg38
NM_001322199 chr9:g.5081821T>C c.1316T>C p.F439S RefSeq GRCh38/hg38
NM_004972 chr9:g.5066779T>C c.1316T>C p.F439S RefSeq GRCh38/hg38
NM_004972.3 chr9:g.5066779T>C c.1316T>C p.F439S RefSeq GRCh38/hg38
NM_001322198 chr9:g.5081821T>C c.1316T>C p.F439S RefSeq GRCh38/hg38
NM_001322199.1 chr9:g.5081821T>C c.1316T>C p.F439S RefSeq GRCh38/hg38
NM_004972.4 chr9:g.5066779T>C c.1316T>C p.F439S RefSeq GRCh38/hg38
NM_001322195 chr9:g.5066779T>C c.1316T>C p.F439S RefSeq GRCh38/hg38

Filtering

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  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References