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Gene | JAK2 |
Variant | W737L |
Impact List | missense |
Protein Effect | unknown |
Gene Variant Descriptions | JAK2 W737L lies within protein kinase domain 1 of the Jak2 protein (UniProt.org). W737L has not been characterized and therefore, its effect on Jak2 protein function is unknown (PubMed, Mar 2025). |
Associated Drug Resistance | |
Category Variants Paths |
JAK2 mutant JAK2 W737L |
Transcript | NM_004972.4 |
gDNA | chr9:g.5080307G>T |
cDNA | c.2210G>T |
Protein | p.W737L |
Source Database | RefSeq |
Genome Build | GRCh38/hg38 |